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According to George O. Curme (Grammar of the English Language in 2 volumes)
'however' is an adversative conjunction ("connecting two members, but
contrasting their meaning") and you can put it just about anywhere you
please. He offers:
'However, as a mother I shall not give up hope' or 'As a mother, however, I
shall not give up hope' or 'As a mother I shall not give up hope, however.'
Fowler* points out that 'however' throws a strong emphasis on the subject of
the sentence if it comes directly after a subject placed first in the
sentence. For example: 'He, however, did not want to give in.' If the
preceeding sentence was something like: 'She was willing to compromise,' the
placement of 'however' is correct, here, because it contrasts her position
with his. On the other hand, if the first sentence was: 'He was willing to
talk,' the placement of 'however' in the following sentence should be: 'He
did not, however, want to give in,' as 'however' placed between the two
parts of the verb will make the difference between what he was and was not
willing to do. (That's my example, not Fowler's.)